Product Info
BioReactor
MRF Reactor
Code No.：
Rotating type mixer for cell culture equipped with an MR210Bio impeller as a standard
・Exhibits high mixing performance at low shear
・Simple shape with excellent washing ability
・Completely compatible with fluid surface fluctuation
・The same culture results as in the laboratory can be reproduced during scale-up too.
The “MR210Bio” impeller developed exclusively for cell culture produces a high circulating flow that runs from the low-pressure area at the bottom of the blades, where the mixing homogeneity inside the tank is high, toward the top of the tank.
Here we show the cell viability in the later stage of the culture under the batch cell culture condition for the turbine type (flat turbine) and wide paddle type (elephant ear) impellers used in the conventional rotating type BioReactor. It can be confirmed that the MRF reactor maintains a higher cell viability than the other conventional impellers in the later stage of the culture.
Features
Development, Customization, and Single-use support of Exclusive Reactor in Accordance with Requirements Specifications
The MRF Reactor is a BioReactor for laboratory use that aim at actual production and scaling up. In addition to a “Simple shape with excellent cleaning ability” that is important for the actual equipment, the “MR210Bio impeller used exclusively for cell culture” that exhibits excellent mixing and homogenizing performance is provided as a standard, and therefore, similar culture results as during laboratory experiments can be reproduced during scale-up too. Moreover, fluid surface fluctuation (fed-batch culture) is supported, because of which the same mixing performance is exhibited no matter how much the liquid volume. A wide range of liquid volumes from small volumes like 1.5 L to large volumes of 20,000 l can be supported.With the help of the dedicated controller “S-BOX × 10α II”, changes in various parameters including PI control can be easily performed.
Specifications
| Model | MRF-3000 / MRF-8000 / MRF-10000 |
|---|---|
| Temperature control method | Band heater (PID control) with anti-excessive temperature rise function (Max. 80 ℃) |
| Power transmission | Magnet drive non-sealing type |
| Gas supply device | Shirasu porous glass (SPG) membrane type / sintered metal type |
| Temp. control range | Room temperature + 5 to 20℃ (normally set to 37℃) |
| Temp. accuracy | ±0.3℃（37℃） |
| Rotation speed range | 5 to 200 r/min |
| Temp. setting | Digital setting, data output 1 - 5 V |
| Speed setting | Touch panel input, data output 0 - 10 V |
| Band heater | 160 W (MRF-3000) 480 W (MRF-8000/10000) |
| Mixer motor | Max. output 100 W |
| Mixing impellers | [Standard] MR210Bio impeller |
| Culture tank Dimensions | I.D. 140 x Depth 203 mm (MRF-3000) I.D. 200 x Depth 330 mm (MRF-8000) I.D. 200 x Depth 360 mm (MRF-10000) |
| Culture tank Total capacity | 3 L (MRF-3000) 8 L (10% dish bottom head. MRF-8000) 10 L (MRF-10000) |
| Environment temp. range | 10 to 35℃ |
| Outer dimensions | W360×H905×D485 mm |
| Weight | approx. 30 kg (MRF-3000) approx. 34 kg (MRF-8000/10000) |
| Power supply | AC 100 V, 50/60 Hz |
| *The performance is the value under room temperature 20℃, power supply AC 100 V, 50 Hz and no load condition. | |