Product Info


VMF Reactor

Code No.:

Animal cell BioReactor VMF Reactor. Vertical reciprocating motion type mixer for cell culture


Development, Customization, and Single-use support of Exclusive Reactor in Accordance with Requirements Specifications
The VMF Reactor is a vertical reciprocating motion type next-generation reciprocating mixer for cell culture that combines together excellent blending performance and gentle mixing. Unlike the general rotating type, severe shear stress control is possible. Moreover, a “completely enclosed structure” that does not require a complex rotating-axis seal mechanism is implemented. There is no threat of contamination or leakage, and it has a high level of sterility and cleanliness.
With the help of the dedicated controller “S-BOX × 10α II”, changes in various parameters including PI control can be easily performed. Through customization, up to eight machines in series are supported.
Control of the shearing action and a good mixing action are both established, and an environment that is best suited for cell culture is created!!
Comparison of shear stress

■Culture example

Comparison of cell culture by CHO cells

The VMF reactor provides cells with the optimal physical environment in the culture tank, creating a suitable tank environment for cell cultivation compared to rotational BioReactors, maintaining a high rate of living cells compared to MRF reactors.
Although this superior effect is weakened for cells that are resistant to shear damage, this product offers superior performance for cell culture that relies on shear damage. This results in increased productivity.


ModelVMF-500 / VMF-1500 / VMF-3000 / VMF-10000
Temperature control methodBand heater (PID control) with anti-excessive temperature rise function (Max. 80 [℃])
Power transmissionLinear shaft drive non-sealing type
Gas supply deviceSintered metal type *Optional
Temp. control rangeRoom temperature + 5 to 20℃ (normally set to 37℃)
Temp. accuracy±0.3[℃](37[℃])
Max. up/down motion amplitude40[mm]
Max. impeller speed300[mm/s]
Temperature settingDigital setting, data output 1 - 5 [V]
Up/down motion settingTouch panel input, data output 1 - 10 [V]
Band heater60 [W](VMF-500)
105 [W](VMF-1500)
160 [W](VMF-3000)
480 [W](VMF-10000)
Mixer motorMax. power 800 [W]
Mixing impellers[Standard] VM200(VMF-500)
[Standard] VM100+VM200(VMF-1500/3000/10000)
Culture tank Dimensions/Total capacityI.D. 90 x Depth 200 [mm] / 0.5[L](VMF-500)
I.D. 110 x Depth 169 [mm] / 1.5[L] (VMF-1500)
I.D. 140 x Depth 203 [mm] / 3[L] (VMF-3000)
I.D. 200 x Depth 360 [mm] / 10[L] (VMF-10000)
Environment temp. range10 to 35[℃]
Outer dimensionsW360×H905×D485 [mm]
Weightapprox. 28[kg] (VMF-500/1500)
approx. 30[kg] (VMF-3000)
approx. 34[kg] (VMF-10000)
Power supplyAC 100[V], 50/60[Hz]
*The performance is the value under room temperature 20℃, power supply AC 100 [V], 50 [Hz] and no load condition.

Related Products

Culture controller for Bioreactor | | S-BOX×10αII
With the help of the dedicated controller “S-BOX × 10α II”, changes in various parameters including PI control can be easily performed.
■Display range/accuracy:pH: 0.00 to 14.00 [pH]
DO (Dissolved oxygen): 0.00 to 20.00 [mg/L]
FL (O2flow rate): 0.00 to 20.00 [mL/min]
Display accuracy: F.S±0.5 [%] ■Setting range:pH (Hydrogen ion concentration): 0.00 to 14.00 [pH]
DO: 0.00 to 10.00 [mg/L]
FL (O2 flow rate): 0.00 to 20.00 [mL/min]
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