Product Info
BioReactor
VMF Reactor
Code No.：
Animal cell BioReactor VMF Reactor. Vertical reciprocating motion type mixer for cell culture
Features
Development, Customization, and Single-use support of Exclusive Reactor in Accordance with Requirements Specifications
The VMF Reactor is a vertical reciprocating motion type next-generation reciprocating mixer for cell culture that combines together excellent blending performance and gentle mixing. Unlike the general rotating type, severe shear stress control is possible. Moreover, a “completely enclosed structure” that does not require a complex rotating-axis seal mechanism is implemented. There is no threat of contamination or leakage, and it has a high level of sterility and cleanliness.With the help of the dedicated controller “S-BOX × 10α II”, changes in various parameters including PI control can be easily performed. Through customization, up to eight machines in series are supported.
Control of the shearing action and a good mixing action are both established, and an environment that is best suited for cell culture is created!!
■Comparison of shear stress
■Culture example
Comparison of cell culture by CHO cells
The VMF reactor provides cells with the optimal physical environment in the culture tank, creating a suitable tank environment for cell cultivation compared to rotational BioReactors, maintaining a high rate of living cells compared to MRF reactors.
Although this superior effect is weakened for cells that are resistant to shear damage, this product offers superior performance for cell culture that relies on shear damage. This results in increased productivity.
Specifications
| Model | VMF-500 / VMF-1500 / VMF-3000 / VMF-10000 |
|---|---|
| Temperature control method | Band heater (PID control) with anti-excessive temperature rise function (Max. 80 [℃]) |
| Power transmission | Linear shaft drive non-sealing type |
| Gas supply device | Sintered metal type *Optional |
| Temp. control range | Room temperature + 5 to 20℃ (normally set to 37℃) |
| Temp. accuracy | ±0.3[℃]（37[℃]） |
| Max. up/down motion amplitude | 40[mm] |
| Max. impeller speed | 300[mm/s] |
| Temperature setting | Digital setting, data output 1 - 5 [V] |
| Up/down motion setting | Touch panel input, data output 1 - 10 [V] |
| Band heater | 60 [W](VMF-500) 105 [W](VMF-1500) 160 [W](VMF-3000) 480 [W](VMF-10000) |
| Mixer motor | Max. power 800 [W] |
| Mixing impellers | [Standard] VM200(VMF-500) [Standard] VM100+VM200(VMF-1500/3000/10000) |
| Culture tank Dimensions/Total capacity | I.D. 90 x Depth 200 [mm] / 0.5[L](VMF-500) I.D. 110 x Depth 169 [mm] / 1.5[L] (VMF-1500) I.D. 140 x Depth 203 [mm] / 3[L] (VMF-3000) I.D. 200 x Depth 360 [mm] / 10[L] (VMF-10000) |
| Environment temp. range | 10 to 35[℃] |
| Outer dimensions | W360×H905×D485 [mm] |
| Weight | approx. 28[kg] (VMF-500/1500) approx. 30[kg] (VMF-3000) approx. 34[kg] (VMF-10000) |
| Power supply | AC 100[V], 50/60[Hz] |
| *The performance is the value under room temperature 20℃, power supply AC 100 [V], 50 [Hz] and no load condition. | |
Related Products
Culture controller for Bioreactor | | S-BOX×10αII
With the help of the dedicated controller “S-BOX × 10α II”, changes in various parameters including PI control can be easily performed.■Display range/accuracy：pH: 0.00 to 14.00 [pH]
DO (Dissolved oxygen): 0.00 to 20.00 [mg/L]
FL (O2flow rate): 0.00 to 20.00 [mL/min]
Display accuracy: F.S±0.5 [%] ■Setting range：pH (Hydrogen ion concentration): 0.00 to 14.00 [pH]
DO: 0.00 to 10.00 [mg/L]
FL (O2 flow rate): 0.00 to 20.00 [mL/min]